We are co-sponsoring a Fire Side Chat Event Open to the First 100 to RSVP this April 2nd at 4pm PST. This is specific to those interested or already working with salivary hormone data collected with the large (11,880 adolescents) Adolescent Brain Cognitive Development (R) Study in the US. Join IISBR’s very own Kristina Uban at this fun round table and networking event!
Developmental Psychobiology: Call for Submissions
Advances and New Approaches to the Study of Stress, Early Experiences, and
Developmental (SEED) Science
This is an open call for submissions for a special issue on “Advances and New Approaches to the Study of Stress, Early Experiences, and Developmental (SEED)
Science” in Developmental Psychobiology. This special issue will be co-edited by Dr. Sarah Watamura and Dr. Erika Manczak.
We invite submissions across a range of topics that highlight innovative or important approaches to understanding the roles of stress, early experiences, and development in typical and disadvantaged environments. We are particularly interested in papers that emphasize mechanisms and processes that occur from the prenatal to adolescent period, including (but not limited to): genetic regulation and epigenetic modification, immune system functioning, hypothalamic pituitary adrenal axis and/or autonomic nervous system regulation, the microbiome, and markers of oxidative stress, or that utilize large-scale data analysis (‘Big Data’) techniques to explore developmental psychobiological questions. We welcome research articles, research reviews, and brief reports. Interested authors should submit an abstract (250 words) to the editors that summarizes their proposed manuscript. From these abstracts, articles will be selected for full submission.
Abstracts are due by May 15, 2019; authors will be notified by June 1, 2019 regarding invitations for a full submission (due September 1, 2019). Publication date is expected for 2020. Please submit abstracts to the Developmental Psychobiology editorial office (firstname.lastname@example.org).
Friendship network position and salivary cortisol levels
|Olga Kornienko, PhD
Katherine H. Clemans, PhD
Dorothée Out, PhD
Douglas A. Granger, PhD
|This study employed a social network analysis approach to examine the associations between friendship network position and cortisol levels. The sample consisted of 74 first-year students from a highly competitive, accelerated Nursing program. Participants completed questionnaires online, completed a series of sociometric nominations, and donated a saliva sample, which was later assayed for cortisol. Metrics derived from directed friendship nominations indexed each student’s friendship network status regarding popularity, gregariousness, and degree of interconnectedness. Results revealed that individuals with lower gregariousness status had higher cortisol levels, and individuals with higher popularity status had higher cortisol levels. Implications for prevailing theories of the social determinants of individual differences in biological sensitivity and susceptibility to context are discussed.|
Salivary diagnostics for pathogens of clinical significance in childhood environmental enteropathy
Principal Investigator: Margaret N. Kosek
Location: Iquitos, Peru
Funded by; Johns Hopkins Fisher Center for Environmental Infectious Diseases Discovery Program
Childhood environmental enteropathy is hypothesized to be a component cause of stunting and is an irreversible condition characterized by abnormal intestinal architecture, decreased nutrient uptake, increased gut permeability, and reduced oral vaccine efficacy. This project will expand salivary diagnostics for future studies of environmental enteropathy as well as other viral, bacterial, and protozoan pathogens that cause significant environmental infectious disease burden.
Salivary Cortisol, Alpha-Amylase & Stress-Induced Telomere Shortening as Pancultural Biomarkers of Health and Aging
Jeffrey G. Snodgrass
David G. Maranon
Susan M. Bailey
Government Postgraduate College
Colorado State University
Research links psychosocial stress to premature telomere shortening and accelerated human aging; however, this association has only been demonstrated in so-called “WEIRD” societies (Western, educated, industrialized, rich, and democratic), where stress is typically lower and life expectancies longer. By contrast, we examine stress and telomere shortening in a non-Western setting among a highly stressed population with overall lower life expectancies: poor indigenous people—the Sahariya—who were displaced (between 1998 and 2002) from their ancestral homes in a central Indian wildlife sanctuary. In this setting, we examined adult populations in two representative villages, one relocated to accommodate the introduction of Asiatic lions into the sanctuary (n = 24 individuals), and the other newly isolated in the sanctuary buffer zone after their previous neighbors were moved (n = 22). Our research strategy combined physical stress measures via the salivary analytes cortisol and α-amylase with self-assessments of psychosomatic stress, ethnographic observations, and telomere length assessment [telomere–fluorescence in situ hybridization (TEL-FISH) coupled with 3D imaging of buccal cell nuclei], providing high-resolution data amenable to multilevel statistical analysis. Consistent with expectations, we found significant associations between each of our stress measures—the two salivary analytes and the psychosomatic symptom survey—and telomere length, after adjusting for relevant behavioral, health, and demographic traits. As the first study (to our knowledge) to link stress to telomere length in a non-WEIRD population, our research strengthens the case for stress-induced telomere shortening as a pancultural biomarker of compromised health and aging.
Responses of Cortisol and Alpha Amylase to Relocation in 1.7 California Sea Lions (Zalophus californianus)
Michelle Farmerie MAIS
Pittsburgh Zoo & PPG Aquarium
Previous serum and saliva cortisol studies have been performed in California sea lions (Zalophus californianus) demonstrating that this species exhibits a correlation of cortisol across these measures and that salivary assays are effective. Although sea lions have previously been studied using salivary cortisol, the relationship between diurnal patterns of cortisol and alpha amylase has not been identified. In 2012, 0.4 California sea lions were to be relocated from the Pittsburgh Zoo & PPG Aquarium to The Smithsonian’s National Zoo. 1.3 sea lions of the original Pittsburgh group (1.7 animals total) were to remain in Pittsburgh. This provided the ideal opportunity to first identify and then establish baselines for cortisol and alpha amylase in 1.3 California sea lions at Pittsburgh and then monitor these analytes in 1.3 animals during the day of the relocation and immediately after. In the months after the relocation, collecting data from all 1.7 animals will provide a better understanding of how relocation of animals effects the entire social group. The evaluation of changes in analytes in response to the stress of the relocation will provide valuable information that could contribute to the enhanced health, welfare and captive management of the species.
Development of an Objective Behavioral Assay of Cohesion to Enhance Composition, Task Performance, and Psychosocial Adaptation in Long-Term Work Groups
|Peter G. Roma, Ph.D.|
|Institutes for Behavior Resources and
Johns Hopkins University School of MedicineSteven R. Hursh, Ph.D.
Institutes for Behavior Resources and
Johns Hopkins University School of MedicineProject Description
|This NASA-sponsored research program focuses on small-group composition factors that affect the trajectories of team cohesion, task performance, and biopsychosocial adaptation over time and in response to operational stressors. This project also includes development of assay technology for measurement and behavioral economic modeling of cooperation, productivity, and fairness behaviors in small groups in applied settings, including isolated, confined, and extreme environments such as the European Space Agency’s Concordia Station in Antarctica [http://www.esa.int/Our_Activities/Human_Spaceflight/Concordia], the Hawai’i Space Exploration Analog and Simulation (HI-SEAS) facility [http://hi-seas.org/], and NASA’s Human Exploration Research Analog (HERA) facility [http://www.nasa.gov/sites/default/files/hrp_hera_experiment_information_package.pdf]. The Project Team’s long-standing partnership with IISBR ensures high-quality physiological data to support investigations of the neurohormonal substrates of cohesion, performance, and biopsychosocial adaptation in long-term work groups.|
Bridging the Psychosocial Stress Model with the Embodiment of Illegality: Exploring physiological inflammation and stress among Latina/o immigrants in Phoenix
|Airín D. Martínez, PhD|
|Undocumented status and fear of immigration enforcement remains a persistent psycho-environmental stressor that Latina/o immigrants face. There is little evidence delineating the processes in which sociopolitical environmental conditions shape psychosocial stressors, much less the neuroendocrinological response from such stressors among Latina/o immigrants in the US. The purpose of this project is to examine how Latino immigrants’ social, economic, and political chronic stressors in Phoenix, AZ interact with biomarkers for stress (cortisol and α-amylase) and inflammation (C-reactive protein (CRP), interleukin (IL-1B, IL-6, IL-8), tumor necrosis factor-alpha (TNF-α), which are directly related to CVD.|
Proyecto Las Madres Nuevas / The New Mothers Project
|Linda Luecken PhD
Assistant Professor: Arizona State Universtiy
|Keith Crnic PhD
Foundation Professor and Department Chair:
Arizona State University
|Nancy Gonzales PhD
Professor: Arizona State University
|Las Madres Nuevas is a research study funded by the National Institute of Mental Health. The objective is to learn about how relationships between low-income Mexican American mothers and their children from birth through the first few years of life affect mother’s mental health and the child’s emotional, behavioral, and physical development. The Las Madres Nuevas project also explores how women’s cultural background and strengths influence her adjustment after childbirth.|
Collecting Saliva and Measuring Salivary Cortisol and Alpha-amylase in Frail Community Residing Older Adults via Family Caregivers
|Nancy A. Hodgson PhD
Johns Hopkins University School of Nursing
|Douglas A. Granger PhD
Foundation Professor of Psychology
Director Institute for Interdisciplinary Salivary Bioscience Research
|Salivary measures have emerged in bio-behavioral research that are easy-to-collect, minimally invasive, and relatively inexpensive biologic markers of stress. This article we present the steps for collection and analysis of two salivary assays in research with frail, community residing older adults-salivary cortisol and salivary alpha amylase. The field of salivary bioscience is rapidly advancing and the purpose of this presentation is to provide an update on the developments for investigators interested in integrating these measures into research on aging. Strategies are presented for instructing family caregivers in collecting saliva in the home, and for conducting laboratory analyses of salivary analytes that have demonstrated feasibility, high compliance, and yield quality specimens. The protocol for sample collection includes: (1) consistent use of collection materials; (2) standardized methods that promote adherence and minimize subject burden; and (3) procedures for controlling certain confounding agents. We also provide strategies for laboratory analyses include: (1) saliva handling and processing; (2) salivary cortisol and salivary alpha amylase assay procedures; and (3) analytic considerations.|
- Next Page »