Background: This study examined the role of sleep problems and sleep duration on stress-related HPA axis reactivity among urban, low income adolescents. A total of [Read more…]
University of Nebraska-Lincoln Salivary Bioscience Laboratory (UNL SBL) Joins the Salivary Research Community
We’re proud to add the University of Nebraska-Lincoln Salivary Bioscience Laboratory (UNL SBL) to our network of affiliate institutions. The UNL SBL serves [Read more…]
Infant adrenocortical reactivity and behavioral functioning: Relation to early exposure to maternal intimate partner violence.
Background: Prenatal stress negatively affects fetal development, which in turn may affect infant hypothalamic-pituitary adrenal (HPA) axis regulation and behavioral functioning. We examined effects of exposure to a traumatic stressor in families [intimate partner violence (IPV)] on both infants’ HPA axis reactivity to stress and their internalizing and externalizing behaviors. Structural equation modeling revealed that [Read more…]
Measuring Nerve Growth Factor in Saliva by Immunoassay: A Cautionary Note
Background: Nerve growth factor (NGF), a neurotrophin, modulates a diverse set of physiologic processes in the nervous, immune, and endocrine systems. Studies suggest that NGF can be measured in [Read more…]
Latent trait cortisol (LTC) during pregnancy: Composition, continuity, change, and concomitants.
Background: Individual differences in the activity of the hypothalamic pituitary adrenal (HPA) axis are often operationalized using summary measures of cortisol that are taken to represent stable individual differences. Here we extend our understanding of a novel latent variable approach to [Read more…]
Salivary Bioscience goes to….Mars?
Well, not exactly. It actually just went to a remote location on Hawaii’s Mauna Loa volcano, where an 8-month simulated mission on Mars recently came to a close. The Hawaii Space Exploration Analog and Simulation (HI-SEAS) facility “is a planetary surface exploration analog site at ~8500 feet on the Mauna Loa side of the saddle area on the Big Island of Hawaii,” according to a post on the HI-SEAS website. You can learn more about the missions at hi-seas.org
Faculty Affiliate of the IISBR, Dr. Pete Roma, is among the team of Scientists studying the six-person HI-SEAS Crews as part of a comprehensive research program supported by the National Aeronautics and Space Administration (NASA).
So what role did Salivary Biosicence play on “Mars”? Dr. Roma explains: “We take regular saliva samples throughout all HI-SEAS missions in order to elucidate the neurohormonal mechanisms involved in group cohesion, team performance, and biopsychosocial adaptation over time in mixed-gender Crews in isolated, confined, and extreme (ICE) environments. A better understanding of how these natural mechanisms operate in ICE environments can help mission planners manage the inherent risks of long-duration space exploration, while the underlying scientific knowledge can ultimately support efforts to enhance cooperation and group cohesion in a variety of social and organizational contexts on Earth, including military, business, healthcare, and education.”
Analysis of saliva samples is administered by IISBR’s world-renowned staff, providing the knowledge and skill required to maintain sample integrity. IISBR’s advice and protocols ensure that high quality biological data are delivered, making accurate conclusions possible. “The IISBR’s expert handling of these irreplaceable samples has been critical to the success of this unique and operationally challenging field research.”
Common oxytocin receptor gene variant interacts with rejection sensitivity to influence cortisol reactivity during negative evaluation
Background: The study tested the hypothesis that variation in the oxytocin receptor gene (OXTR rs53576) and self-report of rejection sensitivity are associated with adrenocortical reactivity to social stress. Our findings suggest [Read more…]
Emotional Reactivity and Parenting Sensitivity Interact to Predict Cortisol Output in Toddlers.
Background: Cortisol output in response to emotion induction procedures was examined at child age 24 months in a prospective longitudinal sample of 1,292 children and families in predominantly low-income and nonurban communities in two regions of high poverty in the United States. Multilevel analysis indicated [Read more…]
Gerry Giesbrecht, PhD, Receives Canadian Institutes of Health Research and Social Sciences and Humanities Research Council Grants
IISBR faculty affiliate Dr. Gerry Giesbrecht recently leveraged his in-depth expertise and research experience to obtain two major Canadian health grants, facilitating research on [Read more…]
Salivary Uric Acid analysis now available through IISBR bioanalytical assay services
This week, Salivary Uric Acid was introduced as the newest addition to the IISBR saliva test menu. Investigators now have the opportunity to assess uric acid levels in saliva in association with many common health issues. [Read more…]
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