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Common oxytocin receptor gene variant interacts with rejection sensitivity to influence cortisol reactivity during negative evaluation

April 21, 2016 by IISBR

Background: The study tested the hypothesis that variation in the oxytocin receptor gene (OXTR rs53576) and self-report of rejection sensitivity are associated with adrenocortical reactivity to social stress. Our findings suggest a curvilinear relationship between social rejection sensitivity and cortisol reactivity in the context of social rejection, warranting further consideration in future studies.

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UCI School of Social Ecology
Social Ecology I
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www.socialecology.uci.edu

UCI Program in Public Health
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www.uci.edu www.publichealth.uci.edu

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