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Salivary Uric Acid analysis now available through IISBR bioanalytical assay services

April 21, 2016 by IISBR

This week, Salivary Uric Acid was introduced as the newest addition to the IISBR saliva test menu. Investigators now have the opportunity to assess uric acid levels in saliva in association with many common health issues.

As a biomarker of great potential, scientific literature searches for uric acid yield 300,000+ publications, citing uric acid’s influences on nearly every major and minor biological system of the body. However, the full picture of uric acid’s effects on health and wellness has yet to be painted. Although gout and kidney stones are most commonly associated with uric acid levels, evidence has also linked uric acid to BMI and obesity, type 2 diabetes, metabolic syndrome, cardiovascular disease, cystic fibrosis, and renal diseases.

As the most abundant antioxidant in the blood, studies have shown uric acid to be a powerful signaling molecule securing its role as a valuable antioxidant. This role further seeks to define uric acid as an important biomarker of oxidative stress. However, further research is still needed to more-clearly define this relationship.
Other common associations include Fanconi syndrome, Lesch-Nyhan syndrome, coronary artery disease, hyperuricemia, dementia, optic neuritis, hypouricemia, preeclampsia, prehypertension, uric acid kidney stones, Parkinson’s disease, kidney disease, antioxidant activity, and gout.

A new advancement in the salivary bioscience research community, with a reported 0.84 serum-saliva correlation, that makes efficient examination of systemic levels possible. With Salivary Uric Acid’s potential combined with IISBR’s experienced technicians performing assay services for your research, investigators can now explore a unique and efficient ability to monitor uric acid levels in saliva and gain in-depth knowledge of its biological effects.

 

Contact the IISBR to add salivary uric acid to your research

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Recent Publications

  • Kimonis, E. R., et al. (2018). Dehydroepiandrosterone (DHEA) and its ratio to cortisol moderate associations between maltreatment and psychopathology in male juvenile offenders. Psychoneuroendocrinology.
  • Gatzke-Kopp, L. M., et al. (2018). Magnitude and Chronicity of Environmental Smoke Exposure Across Infancy and Early Childhood in a Sample of Low-Income Children. Nicotine Tob Res.
  • Pisanic, N., et al. (2018). Minimally Invasive Saliva Testing to Monitor Norovirus Infection in Community Settings. J Infect Dis.
  • Affifi, T. D., et al. (2018). Testing the theory of resilience and relational load (TRRL) in families with type I diabetes. Health Commun.
  • Wheelock, M.D., et al. (2018). Psychosocial stress reactivity is associated with decreased whole brain network efficiency and increased amygdala centrality. Behav Neurosci.
  • Kornienko, O., et al. (2018). Associations Between Secretory Immunoglobulin A and Social Network Structure. Int J Behav Med.
  • Kuhlman, K. R., et al. (2018). Interparental conflict and child HPA-axis responses to acute stress: Insights using intensive repeated measures. J Fam Psychol.
  • Kuhlman, K. R., et al. (2018). HPA-Axis Activation as a Key Moderator of Childhood Trauma Exposure and Adolescent Mental Health. Journal of abnormal child psychology.
  • Corey-Bloom, J., et al. (2018). Salivary levels of total huntingtin are elevated in Huntington’s disease patients. Sci Rep.
  • Martinez, A. D., et al. (2018). Household fear of deportation in Mexican-origin families: Relation to body mass index percentiles and salivary uric acid. Am J Hum Biol.
  • Lucas, T., et al. (2018). Justice for all? Beliefs about justice for self and others and telomere length in African Americans. Cultur Divers Ethnic Minor Psychol.
  • Woerner, J., et al. (2018). Salivary uric acid: Associations with resting and reactive blood pressure response to social evaluative stress in healthy African Americans. Psychoneuroendocrinology.
  • Riis J.L., et al. (2018). The validity, stability, and utility of measuring uric acid in saliva. Biomark Med.

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