This week, Salivary Uric Acid was introduced as the newest addition to the IISBR saliva test menu. Investigators now have the opportunity to assess uric acid levels in saliva in association with many common health issues.

As a biomarker of great potential, scientific literature searches for uric acid yield 300,000+ publications, citing uric acid’s influences on nearly every major and minor biological system of the body. However, the full picture of uric acid’s effects on health and wellness has yet to be painted. Although gout and kidney stones are most commonly associated with uric acid levels, evidence has also linked uric acid to BMI and obesity, type 2 diabetes, metabolic syndrome, cardiovascular disease, cystic fibrosis, and renal diseases.

As the most abundant antioxidant in the blood, studies have shown uric acid to be a powerful signaling molecule securing its role as a valuable antioxidant. This role further seeks to define uric acid as an important biomarker of oxidative stress. However, further research is still needed to more-clearly define this relationship.
Other common associations include Fanconi syndrome, Lesch-Nyhan syndrome, coronary artery disease, hyperuricemia, dementia, optic neuritis, hypouricemia, preeclampsia, prehypertension, uric acid kidney stones, Parkinson’s disease, kidney disease, antioxidant activity, and gout.

A new advancement in the salivary bioscience research community, with a reported 0.84 serum-saliva correlation, that makes efficient examination of systemic levels possible. With Salivary Uric Acid’s potential combined with IISBR’s experienced technicians performing assay services for your research, investigators can now explore a unique and efficient ability to monitor uric acid levels in saliva and gain in-depth knowledge of its biological effects.

 

Contact the IISBR to add salivary uric acid to your research