25
Apr 18
Prenatal and postnatal cigarette and cannabis exposure: Effects on Secretory Immunoglobulin A in early childhood.
Secretory Immunoglobulin A (SIgA) plays a critical role in immune functioning by preventing pathogens from adhering to epithelial mucosa. Most infectious agents enter the body via mucosal surfaces, thus SIgA serves in the...
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16
Apr 18
Early adversity and internalizing symptoms in adolescence: Mediation by individual differences in latent trait cortisol.
Research suggests that early adversity places individuals at risk for psychopathology across the life span. Guided by concepts of allostasis and allostatic load, the present study examined...
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7
Apr 18
Peer Networks, Psychobiology of Stress Response, and Adolescent Development
A consistent focus of research has been on understanding how social relationships shape the activity of the biological stress response system. Progress has been made in...
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27
Mar 18
Testosterone and Proactive-Reactive Aggression in Youth: the Moderating Role of Harsh Discipline.
This study tests a biosocial model of the link between testosterone and proactive-reactive aggression in youth at varying levels of...
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17
Mar 18
Anticipatory stress associated with functional magnetic resonance imaging: Implications for psychosocial stress research.
Stress tasks performed during functional magnetic resonance imaging (fMRI) elicit a relatively small cortisol response compared to stress tasks completed in...
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9
Mar 18
Employment Opportunity: Two-Year Postdoctoral Fellowship in Community-Based Early Childhood Prevention Research
The University of Maryland School of Social Work is seeking a postdoctoral fellow to begin no later than September 1, 2018...
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28
Feb 18
Registration for the 48th ISPNE Annual Conference Now Open!
We are thrilled to announce that the website and registration for 48th ISPNE Annual Conference, "Diversity, Health, and Resilience: Taking Science Beyond Discoveries," is now...
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28
Feb 18
Biobehavioral Insights into Adaptive Behavior in Complex and Dynamic Operational Settings: Lessons learned from the Soldier Performance and Effective, Adaptable Response Task.
The purpose of this study was to explore the biobehavioral correlates of adaptive behavior in the context of a standardized laboratory-based mission-relevant challenge...
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24
Feb 18
Attachment-Related Regulatory Processes Moderate the Impact of Adverse Childhood Experiences on Stress Reaction in Borderline Personality Disorder.
In this study, the authors explored whether attachment insecurity moderates the effects of adverse childhood experiences on stress reactivity in the context of...
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19
Feb 18
Emotion regulation and positive affect in the context of salivary alpha-amylase response to pain in children with cancer.
Children with cancer routinely undergo painful medical procedures invoking strong physiological stress responses. Resilience to this pain may be...
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10
Feb 18
An exploratory analysis of the joint contribution of HPA axis activation and motivation to early adolescent depressive symptoms.
is study examines the interactive contribution of the hypothalamic-pituitary-adrenal (HPA) axis and approach-avoidance motivation systems to longitudinal changes in...
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10
Feb 18
Employment Opportunity: Assistant or Associate Professor @ UNL
The University of Nebraska-Lincoln and its Center for Brain, Biology and Behavior (CB3) invite applications for...
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23
Jan 18
Preclinical evaluation of the effect of the combined use of the Ethicon Securestrap® Open Absorbable Strap Fixation Device and Ethicon Physiomesh™ Open Flexible Composite Mesh Device on surgeon stress during ventral hernia repair.
To evaluate whether performing ventral hernia repairs using the Ethicon Physiomesh™ in conjunction with the Ethicon Securestrap® reduces surgical time and surgeon stress levels, compared with....
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19
Nov 17
Prematurity and perinatal adversity effects hypothalamic-pituitary-adrenal axis reactivity to social evaluative threat in adulthood.
This study examined the long-term effects of prematurity and perinatal adversity on individual differences in stress-related reactivity and regulation of the HPA axis. A prospective sample of...
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8
Oct 17
Telomere length and procedural justice predict stress reactivity responses to unfair outcomes in African Americans.
This experiment demonstrates that chromosomal telomere length (TL) moderates response to injustice among African Americans.
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26
Sep 17
Rina Das Eiden, PhD., and Maggie O’Haire, PhD., join extensive list of Faculty Affiliates at the Institute for Interdisciplinary Salivary Bioscience Research.
The IISBR's scientific network of salivary bioscience researchers continues to build momentum through increasing multidisciplinary research expertise. Recently, Rina Das Eiden, PhD., an expert on prenatal and postnatal consequences of alcohol, cocaine and cigarette use by parents, and Maggie O’Haire, PhD., an expert on the unique and pervasive effects of interactions with animals, joined the IISBR as Faculty Affiliates.
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18
Sep 17
Measurement of cortisol in saliva: a comparison of measurement error within and between international academic-research laboratories.
In established-qualified laboratories, measurement error of salivary cortisol is minimal, and inter-laboratory differences in measurement are unlikely to have a major influence on the determined values.
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9
Sep 17
Individual differences in early adolescents’ latent trait cortisol: Interaction of early adversity and 5-HTTLPR
Background: The present study aimed to examine the interaction of 5-HTTLPR and early adversity on trait-like levels of cortisol. A...
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22
Aug 17
New Collaborative Research at the Naval Health Research Center
Our new IISBR Faculty (Kate and Jenna and Beth) and the IISBR staff traveled with Dr. Granger to visit the Naval Health Research Center in Pt Loma, CA. The UCI team spent the day with Dr. Marc Taylor's research...
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13
Aug 17
Long-Term Effects of Prematurity, Cumulative Medical Risk, and Proximal and Distal Social Forces on Individual Differences in Diurnal Cortisol at Young Adulthood.
Background: This study examined the effects of prematurity, cumulative medical risk, and proximal and distal social forces on individual differences...
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3
Aug 17
New gift from the Prentiss Foundation creates research opportunities for Institute for Interdisciplinary Salivary Bioscience Research
A $150,000 gift from the Elisabeth Severance Prentiss Foundation will enable a new direction for the Institute for Interdisciplinary Salivary Bioscience Research: to translate basic scientific research into clinically useful information and methods...
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24
Jul 17
Exposure to intimate partner violence in utero and infant internalizing behaviors: Moderation by salivary cortisol-alpha amylase asymmetry.
Guided by the main tenets of contemporary models of the developmental origins of health and disease, this study evaluated whether individual differences in reactivity of the hypothalamic-pituitary-adrenal (HPA) axis and Sympathetic Nervous System (SNS) moderate the effect of....
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18
Jul 17
Assistant/Associate Professor, Salivary Bioscience and Clinical Psychology
The Department of Psychology and Social Behavior at the University of California, Irvine invites applications for a full-time, tenure‐track or tenured faculty position in Salivary Bioscience and Clinical Psychology. The position will be at the rank of Assistant Professor or Associate Professor. Candidates must have...
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13
Jul 17
Salivary biomarkers for Huntington’s disease
Peripheral biomarkers are greatly needed in the field of neurodegenerative disorders to anticipate onset of disease symptoms, monitor disease progression, and track potential therapeutic effects. HD is a fatal, inherited neurodegenerative disorder caused by...
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27
Jun 17
The “yin and yang” of the adrenal and gonadal systems in elite military men.
We recently established daily, free-living profiles of the adrenal hormone cortisol, the (primarily adrenal) anabolic precursor dehydroepiandrosterone (DHEA) and the (primarily gonadal) anabolic hormone testosterone in elite military...
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15
Jun 17
Social Ecology hires two new faculty members to collaborate with Institute for Interdisciplinary Salivary Bioscience Research
The School of Social Ecology has hired two new assistant professors, Jenna Riis and Kate Kuhlman, to work in...
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11
Jun 17
Anabolic hormone profiles in elite military men: Robust associations with age, stress, and fatigue.
We recently established stable daily profiles of the anabolic hormones dehydroepiandrosterone (DHEA) and testosterone in 57 elite military men. In this follow-on study, we explored associations of salivary anabolic hormone profiles with...
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5
Jun 17
IISBR Affiliate Faculty Peter G. Roma, Ph.D., Accepts Position as Senior Scientist and Director of the Behavioral Health & Performance Laboratory at NASA’s Johnson Space Center
Salivary bioscience researcher and Affiliate Faculty at the Institute for Interdisciplinary Salivary Bioscience Research (IISBR), Peter G. Roma, Ph.D., has accepted a position as Senior Scientist and Director of the Behavioral Health & Performance Laboratory at NASA Johnson Space Center (JSC) in Houston, Texas...
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16
May 17
Development of an oral fluid immunoassay to assess past and recent hepatitis E virus (HEV) infection.
BACKGROUND: Hepatitis E virus (HEV) infection causes significant morbidity and mortality worldwide, particularly among pregnant women. In clinical settings blood-based...
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6
May 17
Granger appointed Chancellor’s Professor
Doug Granger, director of the Institute for Interdisciplinary Salivary Bioscience Research and a professor of psychology and social behavior, public...
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29
Apr 17
Individual differences in the activity of the hypothalamic pituitary adrenal axis: Relations to age and cumulative risk in early childhood.
This study examined individual differences in the function of the hypothalamic-pituitary-adrenal (HPA) axis with regard to age and cumulative risk during challenging laboratory tasks administered at
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18
Apr 17
Adolescent Conflict Appraisals Moderate the Link Between Marital Conflict and Physiological Stress Reactivity
Background: The goal of this study was to advance understanding of how adolescent conflict appraisals contribute uniquely, and in combination...
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5
Apr 17
Adiponectin: Serum-Saliva Associations and Relations with Oral and Systemic Markers of Inflammation.
Background: This study addresses gaps in our understanding about the validity and utility of using salivary adiponectin to index serum...
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13
Feb 17
A genetic risk factor for major depression and suicidal ideation is mitigated by physical activity.
Background: We evaluated associations of five candidate polymorphisms (Bcl1 [rs41423247], -2C/G [rs2070951], COMT [rs737865], Val66Met [rs6265], and 5HTTLPR [biallelic and...
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21
Dec 16
Open PhD Student Position: Developmental Psychobiology Laboratory, University of Calgary
PhD Student Recruitment The Developmental Psychobiology Laboratory at the University of Calgary, Alberta, Canada, is seeking a PhD student to...
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15
Dec 16
Postdoctoral Research Training Program at CU Anschutz Medical Campus
“Developmental Psychopathology, Psychobiology, and Behavior” Program Director: Randy Ross, MD, Scientific Director: Mark Laudenslager, PhD Clinical, Basic, and Translational Neuroscience...
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10
Dec 16
Call for Applications: UC Intercampus Consortium on Health Psychology Seed Grant Funding
Types of Awards: • Cross-campus faculty team awards: 2 - 3 awards, up to $10,000 each. • Cross-campus trainee team...
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7
Dec 16
Diurnal Salivary Alpha-Amylase Dynamics Among Dementia Family Caregivers.
Background: Objective: The study examined diurnal regulation of salivary alpha-amylase (sAA) in association with daily stressors, adult day services (ADS)...
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2
Dec 16
Association between body mass index and salivary uric acid among Mexican-origin infants, youth and adults: Gender and developmental differences.
Background: Uric acid (UA) is the end product of the metabolic breakdown of purine nucleotides. Recent studies have measured UA...
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18
Nov 16
Prefrontal Cortex Activity Is Associated with Biobehavioral Components of the Stress Response
Background: Contemporary theory suggests that prefrontal cortex (PFC) function is associated with individual variability in the psychobiology of the stress...
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9
Nov 16
Perceived Discrimination, Racial Identity, and Multisystem Stress Response to Social Evaluative Threat Among African American Men and Women.
Background: OBJECTIVES: Understanding individual differences in the psychobiology of the stress response is critical to grasping how psychosocial factors contribute...
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2
Nov 16
The hippocampal response to psychosocial stress varies with salivary uric acid level.
Background: Uric acid is a naturally occurring, endogenous compound that impacts mental health. In particular, uric acid levels are associated...
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17
Sep 16
Seminar Event: Ecology becomes biology: A population health perspective on self-regulation and the foundations of health disparities
Wednesday, September 21, 2016 12 PM - 1:15 PM Room 2086 AIRB Speaker: Sara B Johnson, Ph.D., MPH, Associate...
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7
Sep 16
Concurrent and prospective associations between HPA axis activity and depression symptoms in newlywed women.
Background: We investigated the extent to which individual differences in activity of the hypothalamic pituitary adrenal axis (HPA) are associated...
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27
Aug 16
Prenatal Drug Exposure and Adolescent Cortisol Reactivity: Association with Behavioral Concerns.
Background: OBJECTIVE: To examine stress reactivity in a sample of adolescents with prenatal drug exposure (PDE) by examining the consequences...
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6
Aug 16
Use of Pathogen-Specific Antibody Biomarkers to Estimate Waterborne Infections in Population-Based Settings
Background: There is increasing interest in the mechanisms and biomarkers through which physical activity influence health across the lifespan. Studies...
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26
Jul 16
Salivary Biomarkers in Response to an Acute Bout of Exercise Before and After Training Program: Poster
Background: There is increasing interest in the mechanisms and biomarkers through which physical activity influence health across the lifespan. Studies...
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19
Jul 16
UCI News – Spit Personality
Background: In the name of spit science, Dr. Douglas Granger and his colleagues have collected saliva samples from a restless...
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19
Jul 16
Psychobiological influences on maternal sensitivity in the context of adversity.
Background: This study evaluated prospective longitudinal relations among an index of poverty-related cumulative risk, maternal salivary cortisol, child negative affect,...
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6
Jul 16
Salivary latent trait cortisol (LTC): Relation to lipids, blood pressure, and body composition in middle childhood
Background: Adversity experienced early in life has the potential to influence physical health later in life. The stress-health relation may...
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18
Jun 16
Coordination of cortisol response to social evaluative threat with autonomic and inflammatory responses is moderated by stress appraisals and affect.
Background: Recent approaches to stress regulation have emphasized coordination among multiple biological systems. This study builds on evidence that hypothalamic-pituitary-adrenal...
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4
Jun 16
Individual differences in early adolescents’ latent trait cortisol (LTC): Relation to recent acute and chronic stress.
Background: Research suggests that environmental stress contributes to health by altering the regulation of the hypothalamic pituitary adrenal (HPA) axis....
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14
May 16
Coordination of cortisol response to social evaluative threat with autonomic and inflammatory responses is moderated by stress appraisals and affect.
Background: Recent approaches to stress regulation have emphasized coordination among multiple biological systems. This study builds on evidence that hypothalamic-pituitary-adrenal...
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21
Apr 16
Anabolic hormone profiles in elite military men.
Background: We recently characterized the awakening responses and daily profiles of the catabolic stress hormone cortisol in elite military men....
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21
Apr 16
Maternal sensitivity and adrenocortical functioning across infancy and toddlerhood: Physiological adaptation to context?
Background: Theory suggests that early experiences may calibrate the "threshold activity" of the hypothalamus-pituitary-adrenal axis in childhood. Particularly challenging or...
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21
Apr 16
Individual differences in early adolescents’ latent trait cortisol (LTC): Relation to early adversity.
Background: Substantial evidence suggests that youth who experience early adversity exhibit alterations in hypothalamic pituitary adrenal (HPA) axis functioning, thereby...
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21
Apr 16
Integration of network science and salivary bioscience methods offers new paradigm that could augment behavioral, social, and organizational neuroscience research
Background: A recent IISBR study integrated behavioral endocrinology and network science to explore links between hormones and (more…)
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21
Apr 16
Prematurity, Birth Weight, and Socioeconomic Status Are Linked to Atypical Diurnal Hypothalamic-Pituitary-Adrenal Axis Activity in Young Adults.
Background: In a prospective, case-controlled longitudinal design, 180 preterm and fullterm infants who had been enrolled at birth participated in...
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21
Apr 16
Salivary Bioscience supports pair bonding with the Mommies Program and the Kangaroo Mother Care study
Lisa Cleveland, Ph.D., RN, PNP-BC, IBCLC, assistant professor at the University of Texas Health Science Center at San Antonio, School...
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21
Apr 16
Lack of consistent evidence for cortisol dysregulation in premenstrual syndrome/premenstrual dysphoric disorder
Research Highlights: Little evidence of an association between PMS/PMDD and cortisol level/reactivity. Methodological issues do not account for findings of...
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21
Apr 16
Sleep problems predict cortisol reactivity to stress in urban adolescents
Background: This study examined the role of sleep problems and sleep duration on stress-related HPA axis reactivity among urban, low...
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21
Apr 16
University of Nebraska-Lincoln Salivary Bioscience Laboratory (UNL SBL) Joins the Salivary Research Community
We’re proud to add the University of Nebraska-Lincoln Salivary Bioscience Laboratory (UNL SBL) to our network of affiliate institutions. The...
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21
Apr 16
Infant adrenocortical reactivity and behavioral functioning: Relation to early exposure to maternal intimate partner violence.
Background: Prenatal stress negatively affects fetal development, which in turn may affect infant hypothalamic-pituitary adrenal (HPA) axis regulation and behavioral...
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21
Apr 16
Measuring Nerve Growth Factor in Saliva by Immunoassay: A Cautionary Note
Background: Nerve growth factor (NGF), a neurotrophin, modulates a diverse set of physiologic processes in the nervous, immune, and endocrine...
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21
Apr 16
Latent trait cortisol (LTC) during pregnancy: Composition, continuity, change, and concomitants.
Background: Individual differences in the activity of the hypothalamic pituitary adrenal (HPA) axis are often operationalized using summary measures of...
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21
Apr 16
Salivary Bioscience goes to….Mars?
Well, not exactly. It actually just went to a remote location on Hawaii’s Mauna Loa volcano, where an 8-month simulated...
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21
Apr 16
Common oxytocin receptor gene variant interacts with rejection sensitivity to influence cortisol reactivity during negative evaluation
Background: The study tested the hypothesis that variation in the oxytocin receptor gene (OXTR rs53576) and self-report of rejection sensitivity...
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21
Apr 16
Emotional Reactivity and Parenting Sensitivity Interact to Predict Cortisol Output in Toddlers.
Background: Cortisol output in response to emotion induction procedures was examined at child age 24 months in a prospective longitudinal...
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21
Apr 16
Gerry Giesbrecht, PhD, Receives Canadian Institutes of Health Research and Social Sciences and Humanities Research Council Grants
IISBR faculty affiliate Dr. Gerry Giesbrecht recently leveraged his in-depth expertise and research experience to obtain two major Canadian health...
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21
Apr 16
Salivary Uric Acid analysis now available through IISBR bioanalytical assay services
This week, Salivary Uric Acid was introduced as the newest addition to the IISBR saliva test menu. Investigators now have...
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21
Apr 16
IISBR Research Accepted for Presentation at the 45th Annual Conference of International Society for Psychoneuroendocrinology (ISPNE), September 8-11th, Edinburgh Scotland.
Ha, T., Granger, D. A., Shore, D. M., Yeung, E. W., & Dishion, T. J. (September, 2015). ISPNE, Neural responses...
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21
Apr 16
Stress pulls us apart: Anxiety leads to differences in competitive confidence under stress
Background: Social competition is a fundamental mechanism of evolution yet little is known about factors that affect competitive success, especially...
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21
Apr 16
S&R Foundation Launches Sachiko Kuno Award for Applied Science, Dr. Sheila Ohlsson Walker Honored as Inaugural Recipient
IISBR faculty affiliate and salivary bioscience researcher Dr. Sheila Ohlsson Walker was the inaugural recipient of the newly-launched Sachiko Kuno...
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21
Apr 16
Prenatal tobacco exposure and infant stress reactivity: Role of child sex and maternal behavior.
Background: A study was designed to examine the association between prenatal tobacco exposure (PTE) and infant cortisol reactivity of children...
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21
Apr 16
Latent trait cortisol (LTC) levels: Reliability, validity, and stability.
Background: The regulation of hypothalamic pituitary adrenal (HPA) axis contributes to individual differences in health and human development. (more…)
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21
Apr 16
Salivary Cortisol, Alpha-Amylase & Stress-Induced Telomere Shortening as Biomarkers of Health and Aging
Background: Recent research links life stress to premature telomere shortening and human aging. However, this association has only been demonstrated...
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21
Apr 16
Alpha-amylase reactivity in relation to psychopathic traits in adults
Background: In the present study, we examined sAA, in addition to salivary cortisol, in a relatively large sample (more…)
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21
Apr 16
@CanineScience – Thank You!
@CanineScience - Thanks for the shout-out to Dr. Nancy Dreschel and Dr. Douglas Granger for collaborating in research on stress...
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21
Apr 16
Maternal intimate partner violence exposure, child cortisol reactivity and child asthma
Background: Study investigates association between intimate partner violence (IPV) exposure and increased risk of childhood asthma, and assesses whether this...
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20
Apr 16
Maternal Disrupted Communication During Face-to-Face Interaction at 4 months: Relation to Maternal and Infant Cortisol Among at-Risk Families
Background: This study evaluates the association between maternal communication and stress response in infants. Results point to low maternal cortisol...
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20
Apr 16
Maternal-child adrenocortical attunement in early childhood: Continuity and change.
Background: This study evaluated continuity and change in maternal-child hypothalamic-pituitary-adrenal axis attunement in early childhood. Participants were drawn from a...
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20
Apr 16
Harsh discipline and behavior problems: The moderating effects of cortisol and alpha-amylase
Background: This study investigated whether the interaction between hypothalamic-pituitary-adrenal (HPA) activity and autonomic nervous system (ANS) arousal moderated the link...
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20
Apr 16
Study finds no evidence that salivary alpha-amylase or cortisol mediate the relationship between poverty and later behavior problems
Background: This study examined the development of baseline autonomic nervous system (ANS) and hypothalamic-pituitary-adrenal (HPA) physiological activity from (more…)
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20
Apr 16
Taking a Health Hazard Home
Background: A new study of a small group of workers at industrial hog farms in North Carolina has found that...
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20
Apr 16
Parent-child relationship quality moderates the link between marital conflict and adolescents’ physiological responses to social evaluative threat
Background: This study examined how marital conflict and parent-child relationship quality moderate individual differences in adolescents' adrenocortical and autonomic nervous...
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20
Apr 16
Salivary Bioscience is on the move.
Welcome to the University of California Institute for Interdisciplinary Salivary Bioscience Research at UC Irvine. Our laboratories are being constructed...
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