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Early adversity and internalizing symptoms in adolescence: Mediation by individual differences in latent trait cortisol.

April 16, 2018 by IISBR

Background:

Research suggests that early adversity places individuals at risk for psychopathology across the life span. Guided by concepts of allostasis and allostatic load, the present study examined whether early adversity contributes to the development of subsequent internalizing symptoms through its association with traitlike individual differences in hypothalamic-pituitary-adrenal axis regulation. Early adolescent girls (n = 113; M age = 12.30 years) provided saliva samples at waking, 30 min postwaking, and bedtime over 3 days (later assayed for cortisol). Objective contextual stress interviews with adolescents and their mothers were used to assess the accumulation of nine types of early adversity within the family environment. Greater early adversity predicted subsequent increases in internalizing symptoms through lower levels of latent trait cortisol. Traitlike individual differences in hypothalamic-pituitary-adrenal axis activity may be among the mechanisms through which early adversity confers risk for the development of psychopathology.

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Tagged With: adversity, allostasis, allostatic load, HPA axis, Hypothalamic pituitary adrenal axis, latient trait cortisol, psychopathology, salivary cortisol

Peer Networks, Psychobiology of Stress Response, and Adolescent Development

April 7, 2018 by IISBR

From the Oxford Handbook of Evolution, Biology, and Society:

A consistent focus of research has been on understanding how social relationships shape the activity of the biological stress response system. Progress has been made in characterizing these dynamics at the level of the individual, but significantly less is known about the role of social networks as a proximal ecology in which the stress response system is activated and contributes to human development. The focus of this chapter is on adolescence—a developmental period in which social relationships with peers represent both sources of social stress and opportunities for social buffering. It is proposed that considering peer social networks in which adolescents are embedded will augment understanding of the social context of psychosocial processes, including social status, rejection, isolation, bullying and victimization, and support, that are related to psychobiology of stress.

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Tagged With: adolescence, cortisol, Hypothalamic pituitary adrenal axis, peer networks, social buffering, social stressors

Individual differences in early adolescents’ latent trait cortisol (LTC): Relation to recent acute and chronic stress.

June 4, 2016 by IISBR

Background: Research suggests that environmental stress contributes to health by altering the regulation of the hypothalamic pituitary adrenal (HPA) axis. Recent evidence indicates that early life stress alters trait indicators of HPA axis activity, but whether recent stress alters such indicators is unknown. Using objective contextual stress interviews with adolescent girls and their mothers, we examined the impact of recent acute and chronic stress occurring during the past year on early adolescent girls’ latent trait cortisol (LTC) level. We also examined whether associations between recent stress and LTC level: a) varied according to the interpersonal nature and controllability of the stress; and b) remained after accounting for the effect of early life stress. Adolescents (n=117;M age=12.39years) provided salivary cortisol samples three times a day (waking, 30min post-waking and bedtime) over 3days. Results indicated that greater recent interpersonal acute stress and greater recent independent (i.e., uncontrollable) acute stress were each associated with a higher LTC level, over and above the effect of early adversity. In contrast, greater recent chronic stress was associated with a lower LTC level. Findings were similar in the overall sample and a subsample of participants who strictly adhered to the timed schedule of saliva sample collection. Implications for understanding the impact of recent stress on trait-like individual differences in HPA axis activity are discussed.

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Tagged With: Acute stress, Chronic stress, Early adversity, Hypothalamic pituitary adrenal axis, salivary cortisol, Trait

UCI School of Social Ecology
Social Ecology I
Irvine, CA 92697-7050
www.uci.edu
www.socialecology.uci.edu

UCI Program in Public Health
UCI Health Sciences Complex
856 Health Sciences Quad
Irvine, CA 92697-3957
www.uci.edu www.publichealth.uci.edu

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